PETAL model documentation

Model families, training data and downloadable files.

Explore the scientific background behind PETAL. Here you find information for each gene regulatory element type we use, the model architecture used for that element, the Plant STARR-seq data behind it and files needed for reproducibility.

Plant STARR-seq, or how we obtain our training data

Plant STARR-seq is a massively parallel reporter assay (MPRA) that enables high-throughput quantification of gene regulatory element activity.
We have extensively applied Plant STARR-seq to characterize core promoters, enhancers, terminators and silencers.
Combined with advances in deep learning, these rich datasets now provide an opportunity to accurately predict the activity of major gene regulatory elements.

High-level overview of PETAL model documentation.
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An overview of our models.

The sections below are model-family specific: for each DNA type model we give some architecture notes, training-data notes and model-performance information.
Note that PETAL contains main and legacy models: main models are the current productive models we suggest to use. Legacy models are old models we keep for reproducibility.

Have a model you would like to make available through PETAL? Please reach out to me via email to discuss whether and how your model could be integrated into or hosted on PETAL.

Enhancer model

Enhancer activity prediction

PLACEHOLDER section for enhancer models

Model architecture

PLACEHOLDER

STARR-seq training data

PLACEHOLDER

Citations

Architecture citation: TODO STARR-seq data citation: TODO Model citation: TODO

Core promoter model

Core promoter activity prediction

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Model architecture

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STARR-seq training data

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Citations

Architecture citation: TODO STARR-seq data citation: TODO Model citation: TODO

Terminator model

Terminator activity prediction

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Model architecture

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STARR-seq training data

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Citations

Architecture citation: TODO STARR-seq data citation: TODO Model citation: TODO